>SGPL_ARATH (Q9C509) Sphingosine-1-phosphate lyase (EC 4.1.2.27) (SP-lyase)|
           (SPL) (Sphingosine-1-phosphate aldolase)
          Length = 544

 Score =  215 bits (547), Expect = 9e-56
 Identities = 99/136 (72%), Positives = 120/136 (88%)
 Frame = -1

Query: 591 LGLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSK 412
           LG  GYL++T +IME SK++++G+ +I  LFVIGKPDMT+VAFGS A+DIFEVNDIMSSK
Sbjct: 407 LGEEGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDIMSSK 466

Query: 411 GWHLNALQRPNSLHICVTLQHTAIYEEFLKDLEDSVNTVKANPGPISGGMAPIYGAAGKM 232
           GWHLNALQRPNS+HIC+TLQH  + ++FL+DL ++V TVKANPGPI+GG+APIYGAAGKM
Sbjct: 467 GWHLNALQRPNSIHICITLQHVPVVDDFLRDLREAVETVKANPGPITGGLAPIYGAAGKM 526

Query: 231 PDRGTVKELLVEFMDS 184
           PDRG V ELLV FMDS
Sbjct: 527 PDRGMVNELLVSFMDS 542

>SGPL1_HUMAN (O95470) Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase)|
           (hSPL) (Sphingosine-1-phosphate aldolase)
          Length = 568

 Score =  118 bits (295), Expect = 1e-26
 Identities = 57/137 (41%), Positives = 89/137 (64%), Gaps = 2/137 (1%)
 Frame = -1

Query: 588 GLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSKG 409
           G NGY+E+T QI++ ++ ++  +++I G+FV G P ++V+A GS   DI+ ++++M++KG
Sbjct: 412 GENGYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKG 471

Query: 408 WHLNALQRPNSLHICVTLQHT--AIYEEFLKDLEDSVNTVKANPGPISGGMAPIYGAAGK 235
           W+LN LQ P S+H C+TL H    +  +FLKD+ +SV  +  NP   + GM  IYG A  
Sbjct: 472 WNLNQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQT 531

Query: 234 MPDRGTVKELLVEFMDS 184
             DR  V EL   F+DS
Sbjct: 532 TVDRNMVAELSSVFLDS 548

>SGPL1_RAT (Q8CHN6) Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase)|
           (SPL) (Sphingosine-1-phosphate aldolase)
          Length = 568

 Score =  116 bits (291), Expect = 4e-26
 Identities = 55/137 (40%), Positives = 90/137 (65%), Gaps = 2/137 (1%)
 Frame = -1

Query: 588 GLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSKG 409
           G NGY+E+T QI++ ++ ++  +++I  +F++G P ++V+A GS+  DI+ ++++MS+KG
Sbjct: 412 GENGYVEATKQIIKTARFLKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKG 471

Query: 408 WHLNALQRPNSLHICVTLQHT--AIYEEFLKDLEDSVNTVKANPGPISGGMAPIYGAAGK 235
           W+ N LQ P S+H C+TL HT   +  +FLKD+ +SV  +  NP   + GM  IYG A  
Sbjct: 472 WNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQA 531

Query: 234 MPDRGTVKELLVEFMDS 184
             DR  V E+   F+DS
Sbjct: 532 TIDRKMVAEISSVFLDS 548

>SGPL1_MOUSE (Q8R0X7) Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase)|
           (mSPL) (Sphingosine-1-phosphate aldolase)
          Length = 568

 Score =  114 bits (285), Expect = 2e-25
 Identities = 54/136 (39%), Positives = 88/136 (64%), Gaps = 2/136 (1%)
 Frame = -1

Query: 588 GLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSKG 409
           G NGY+E+T QI++ ++ ++  +++I  +F+ G P ++V+A GS+  DI+ ++++MS+KG
Sbjct: 412 GENGYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKG 471

Query: 408 WHLNALQRPNSLHICVTLQHT--AIYEEFLKDLEDSVNTVKANPGPISGGMAPIYGAAGK 235
           W+ N LQ P S+H C+TL HT   +  +FLKD+ +SV  +  NP   + GM  IYG A  
Sbjct: 472 WNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQA 531

Query: 234 MPDRGTVKELLVEFMD 187
             DR  V E+   F+D
Sbjct: 532 TIDRKLVAEISSVFLD 547

>SGPL_DROME (Q9V7Y2) Sphingosine-1-phosphate lyase (EC 4.1.2.27) (SP-lyase)|
           (SPL) (Sphingosine-1-phosphate aldolase)
          Length = 545

 Score =  114 bits (285), Expect = 2e-25
 Identities = 55/138 (39%), Positives = 90/138 (65%), Gaps = 3/138 (2%)
 Frame = -1

Query: 588 GLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSKG 409
           G +GYLE+T +I++ ++ I++G+ DI G+F+ GKP  +V+A GS+  DIF ++D +   G
Sbjct: 401 GYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLG 460

Query: 408 WHLNALQRPNSLHICVTLQHT--AIYEEFLKDLEDSVNTVKANPG-PISGGMAPIYGAAG 238
           W+LNALQ P+ +H+CVT  HT   + ++F+ D+      +  +PG P+ G MA +YG A 
Sbjct: 461 WNLNALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMA-LYGMAQ 519

Query: 237 KMPDRGTVKELLVEFMDS 184
            +PDR  + E+   F+ S
Sbjct: 520 SIPDRSVIGEVTRLFLHS 537

>SGPL_YEAST (Q05567) Sphingosine-1-phosphate lyase (EC 4.1.2.27) (SP-lyase)|
           (ySPL) (Sphingosine-1-phosphate aldolase) (Bestowed of
           sphingosine tolerance 1)
          Length = 589

 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 49/139 (35%), Positives = 82/139 (58%), Gaps = 3/139 (2%)
 Frame = -1

Query: 591 LGLNGYLESTGQIMEVSKKIQKGI-DDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSS 415
           +G NGY+ES  +I+  + K +K I ++I  L ++G P  +V++F S  ++I E++D +S 
Sbjct: 438 MGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSK 497

Query: 414 KGWHLNALQRPNSLHICVTLQHTAIYEEFLKDLEDSVNTVK--ANPGPISGGMAPIYGAA 241
           KGWH NALQ+P +LH+  T     + +E    L  +V  +K  +N  P   G + +YG A
Sbjct: 498 KGWHFNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVA 557

Query: 240 GKMPDRGTVKELLVEFMDS 184
           G +   G   +L+V F+D+
Sbjct: 558 GSVKTAGVADKLIVGFLDA 576

>SGPL_CAEEL (Q9Y194) Sphingosine-1-phosphate lyase (EC 4.1.2.27) (SP-lyase)|
           (SPL) (Sphingosine-1-phosphate aldolase)
          Length = 552

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 44/139 (31%), Positives = 79/139 (56%), Gaps = 3/139 (2%)
 Frame = -1

Query: 588 GLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSKG 409
           G + Y+    QI++ ++ + + I+ I  +   GK D+++VAF  + V+I+EV+D M   G
Sbjct: 406 GRDEYVRRCAQIVKHTRMLAEKIEKIKWIKPYGKSDVSLVAFSGNGVNIYEVSDKMMKLG 465

Query: 408 WHLNALQRPNSLHICVTLQ--HTAIYEEFLKDLEDSVNTVKA-NPGPISGGMAPIYGAAG 238
           W+LN LQ P ++HIC+T+   +  +   F  DLE     + A        GMA +YG A 
Sbjct: 466 WNLNTLQNPAAIHICLTINQANEEVVNAFAVDLEKICEELAAKGEQKADSGMAAMYGMAA 525

Query: 237 KMPDRGTVKELLVEFMDSS 181
           ++P +  V E++  ++D++
Sbjct: 526 QVP-KSVVDEVIALYIDAT 543

>MFNA_PYRKO (Q5JJ82) L-tyrosine decarboxylase (EC 4.1.1.25) (TDC)|
          Length = 384

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 25/94 (26%), Positives = 55/94 (58%)
 Frame = -1

Query: 591 LGLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSK 412
           LG +GY E   + ME+++     +  I G+++I +P + +V+FGS+ ++  E+   + ++
Sbjct: 289 LGFDGYKEVVKEKMELARWFASELKKIPGIYLIREPVLNIVSFGSEKLE--ELEKELKAR 346

Query: 411 GWHLNALQRPNSLHICVTLQHTAIYEEFLKDLED 310
           GW ++A +    + +   ++   + EEFL+DL +
Sbjct: 347 GWGVSAHRGYIRIVVMPHVKREHL-EEFLRDLRE 379

>MFNA_METTH (O27188) L-tyrosine decarboxylase (EC 4.1.1.25) (TDC)|
          Length = 363

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 26/97 (26%), Positives = 53/97 (54%), Gaps = 4/97 (4%)
 Frame = -1

Query: 591 LGLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSK 412
           +G  GY +   ++M V+++++ G+ ++    V+ +P++ +VAF   A+   E+ D +   
Sbjct: 264 MGREGYRKLALRVMGVTRRLRDGLVELDYQLVV-EPELNIVAFNHPAMGPHELADRLEEL 322

Query: 411 GWHLNALQRPNSLHICVTLQHTAIYEE----FLKDLE 313
           GW ++    P ++ + V + H  I EE     L+DLE
Sbjct: 323 GWAVSVSSCPPAIRV-VLMPH--IMEEHIELLLRDLE 356

>DCE_LYCES (P54767) Glutamate decarboxylase (EC 4.1.1.15) (GAD) (ERT D1)|
          Length = 502

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 5/99 (5%)
 Frame = -1

Query: 591 LGLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKP-DMTVVAFG---SDAVDIFEVNDI 424
           LG  GY       +  +K + +GI  +    ++ K   + VVAF    S    +FEV++ 
Sbjct: 336 LGFEGYKNVMKNCLSNAKVLTEGITKMGRFDIVSKDVGVPVVAFSLRDSSKYTVFEVSEH 395

Query: 423 MSSKGWHLNA-LQRPNSLHICVTLQHTAIYEEFLKDLED 310
           +   GW + A    P++ HI V      I E+F   L +
Sbjct: 396 LRRFGWIVPAYTMPPDAEHIAVL--RVVIREDFSHSLAE 432

>DCE1_ARATH (Q42521) Glutamate decarboxylase 1 (EC 4.1.1.15) (GAD 1)|
          Length = 502

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
 Frame = -1

Query: 591 LGLNGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPD-MTVVAFG---SDAVDIFEVNDI 424
           LG  GY        E    +++G++      ++ K + + +VAF    S     FE++D+
Sbjct: 335 LGHEGYRNVMENCRENMIVLREGLEKTERFNIVSKDEGVPLVAFSLKDSSCHTEFEISDM 394

Query: 423 MSSKGWHLNA-LQRPNSLHICVTLQHTAIYEEFLKDLED 310
           +   GW + A    PN+ HI  T+    I E+F + L +
Sbjct: 395 LRRYGWIVPAYTMPPNAQHI--TVLRVVIREDFSRTLAE 431

>SMG1_CAEBR (Q61CW2) Serine/threonine-protein kinase smg-1 (EC 2.7.11.1)|
           (Suppressor with morphogenetic effect on genitalia
           protein 1)
          Length = 2319

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
 Frame = +1

Query: 187 VHELYK*LLDRASIRHLPSRPVDRSHPPADRP------WIRFHGVYRILEILEEFLVN 342
           +  L K +++R S    P    +   PPA  P      W+R H + +++E+LE+ +++
Sbjct: 776 IKRLAKEVINRKSSDKKPKSTTEDVPPPATPPLKFSIQWLRVHLLLKLIEVLEKIMIS 833

>Y087_DEIRA (Q9RY63) UPF0168 protein DR0087|
          Length = 157

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 16/35 (45%), Positives = 19/35 (54%)
 Frame = +1

Query: 265 PPADRPWIRFHGVYRILEILEEFLVNCRVLKCHAD 369
           P  D  +IRF  VYR  + LE F+   R LK H D
Sbjct: 115 PLDDVAYIRFASVYRDFDSLERFIEEIRGLKGHED 149

>SYFB_BACSK (Q5WEJ6) Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20)|
           (Phenylalanine--tRNA ligase beta chain) (PheRS)
          Length = 808

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
 Frame = -1

Query: 582 NGYLESTGQIMEVSKKIQKGIDDISGLFVIGKPDMTVVAFGSDAVDIFEVNDIMSSKGWH 403
           NG + S  ++   SK + KG  D  G++V   P+   V  G DA+ IFE+ND +      
Sbjct: 117 NGMICSLQELGIDSKLVPKGYVD--GIYVF--PETQSVEPGQDALAIFELNDSVLELDLT 172

Query: 402 LNALQRPNSLHIC-VTLQHTAIYEEFLKDLEDSVNTV 295
            N   R + +H+  V  +  A+Y+  +K  +  V  V
Sbjct: 173 PN---RSDCMHMLGVAYELAALYDRPIKMPKTKVKEV 206

>IFRD2_HUMAN (Q12894) Interferon-related developmental regulator 2 (SKMC15|
           protein)
          Length = 442

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 15/34 (44%), Positives = 19/34 (55%)
 Frame = +3

Query: 411 LLMTLCHSPQICRPRPTQRPRQSCLVSQSQINLR 512
           LL+T+C S QI      Q PR   L+S   +NLR
Sbjct: 244 LLLTICPSTQISHILDRQLPRLPQLLSSESVNLR 277


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,135,241
Number of Sequences: 219361
Number of extensions: 1872895
Number of successful extensions: 4953
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4803
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4946
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 5158951200
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)